Customization: | Available |
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Environmental Protection: | Yes |
Certification: | GMP |
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Basic Information:
English name: Bakuchiol
Cas : 10309-37-2
MF: C18H24O
MW 256.389
Source: Psoralea corylifolia Linn.
Physical properties: Oil
Purity: 90%
Analytical method: HPLC-DAD or/and HPLC-ELSD
Product Description:
Psoralen, isopsoralen and 8-methoxypsoralen are photosensitive substances in Psoralea corylifolia. Therefore, UVA combined with sunshine or topical irradiation can promote the formation of skin melanin. Psoralea corylifolia can activate tyrosinase up to 44.9%. Psoralea corylifolia extract of 95% ethanol has obvious activation on tyrosinase, and tyrosinase is the key enzyme of melanin synthesis in human body. Therefore, Psoralea corylifolia can increase the speed and quantity of melanin production by increasing the activity of tyrosinase. Psoralen B can dilate blood vessels, improve local tissue nutrition, increase skin pigmentation, promote the synthesis of skin melanin, and make it sink to the subcutaneous.
Function:
1. The vitiligo liniment composed of psoralen, plum, Angelica dahurica, cinnamon and other multiflavor drugs has the function of warming meridians and dredging collaterals, nourishing blood and dispelling wind; while 8-methoxypsoralen 0.05%/ml and acetic acid skin relaxant 0.0125%/ml can be used externally to treat vitiligo, with definite curative effect and good clinical effect.
2. Psoralen tincture, which is mainly prepared by psoralen and isopsoralen, can increase tyrosinase activity in melanocytes, promote biochemical synthesis and operation of melanin, and promote skin color to return to normal.
3.8- methoxalin liposome gel, because MOP rarely entered the blood circulation, reduced many adverse reactions (retinal toxicity and hepatotoxicity), and increased its retention time and retention in the basal layer of epidermis, thus promoting melanin synthesis.
4. Psoralea corylifolia injection contains 8-methoxypsoralen, which can increase the sensitivity of skin to ultraviolet radiation. After ultraviolet irradiation, it can effectively inhibit DNA synthesis of epidermal keratinocytes, thereby inhibiting excessive proliferation of psoriatic keratinocytes and achieving therapeutic purposes.
FAQ
Application Area:
Uridine 5-Mophosphate Disodium are produced through the hydrolytic reaction from Ribonucleic acid(RNA) as raw material by enzymatic catalysis to form four kinds of nucleotides 5- 'AMP (adenosine-5'-monophosphate), 5'-GMP•2Na(guanosine-5'-monophosphate, disodium salt), 5'-CMP(cytidine-5'-monophosphate)-, 5'-UMP•2Na (uridine- 5'-monophosphate,Disodium salt) .By the chromatographic isolation, four kinds of separated 5'-nucleotide products with high purity can be obtained. These products can be widely applied in medicine, reagent, fine chemical industry, and additive of food fields etc.